Evaluation of Rbc Membrane Stabilization and Antioxidant Activity of Bombax Ceiba in an in Vitro Method
نویسنده
چکیده
This study reports the human red blood cells (HRBC) and sheep red blood cells (SRBC) membrane stabilizing property and the antioxidizing property of ethyl acetate soluble fraction of the gynaceum part of Bombax ceiba. The probable mode by which Bombax ceiba mediates its effects on inflammatory conditions was studied on HRBC & SRBC exposed to hypotonic solution. The results of the study revealed that the EtOAc soluble fraction of Bombax ceiba possesses anti-inflammatory property. However, the extract did not have the membrane stabilizing property. The results of the study suggest that the antiinflammatory activity may not be related to membrane stabilization. It failed to show inhibition nature even in the higher concentration during the estimation antioxidizing property.
منابع مشابه
Antibacterial and Antioxidant Potential of Stem Bark Extract of Bombax Ceiba Collected Locally from South Punjab Area of Pakistan
BACKGROUND Ethnic medication systems have been used extensively by humans since their origin. Now a day, in the developing countries these systems are being used due to their effectiveness and affordability. Especially inhabitants of rural areas still rely on these systems as first line of treatment against diseased conditions. Till now, majority of medicines is derived from the natural origin ...
متن کاملAssessment of credibility of some folk medicinal claims on Bombax ceiba L
The present paper is an attempt to assess the credibility of various folk claims on medicinal uses of Bombax ceiba L. in view of scientific studies done so far. Almost all parts of the plant are widely used by tribal communities for gastrointestinal and skin diseases, gynecological and urino-genital disorders, general debility, diabetes and impotence. There are direct evidences of scientific va...
متن کاملEvaluation of Phenolic Content Variability along with Antioxidant, Antimicrobial, and Cytotoxic Potential of Selected Traditional Medicinal Plants from India
Plants have been used since ancient times as an important source of biologically active substances. The aim of the present study was to investigate the phytochemical constituents (flavonoids and phenolics), antioxidant potential, cytotoxicity against HepG2 (human hepato carcinoma) cancer cell lines, and the antimicrobial activity of the methanol extract of selected traditional medicinal plants ...
متن کاملHypotensive activity and toxicology of constituents from Bombax ceiba stem bark.
A novel constituent, shamimicin, 1"', 1"""'-bis-2-(3,4-dihydroxyphenyl)-3,4-dihydro-3,7-dihydroxy-5-O-xylopyranosyloxy-2H-1-benzopyran along with lupeol, which possesses potent hypotensive activity, has been isolated from Bombax ceiba stem bark. BCBMM--one of the most active hypotensive fractions has revealed its adverse effects on heart, liver and kidneys of mice at the dose of 1000 mg/kg/d.
متن کاملAntioxidant and Anti-Inflammatory Properties of Autolysed Extract of the Indian Earthworm Pheretima posthuma after Preliminary Purification - An In Vitro Study
The current study is aimed to investigate and evaluate the therapeutic potential of the dialysed protein extract of the Indian earthworm Pheretima posthuma for antioxidant and anti-inflammatory activities. The antioxidant activity was assessed by calculating Total Phenolic Content, Reducing power and Nitric Oxide Radical Inhibition capacity of the prepared autolysed earthworm extract. The anti-...
متن کامل